Induction of molecular chaperones in carbon tetrachloride–treated rat liver: implications in protection against liver damage
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منابع مشابه
Hepatoprotective activity of aerial parts of Otostegia persica against carbon tetrachloride-induced liver damage in rats
Objective: To evaluate the hepatoprotective properties of Otostegia persica (O. persica) ethanol extract on carbon tetrachloride-induced liver damage in rats. Materials and Methods: Fifty adult male Wistar rats were randomly divided into five groups. Group I served as normal control and was given only olive oil intraperitoneally (i.p.). Group II, III, IV, and V were administered CCl4 mixed wi...
متن کاملAntioxidant and Hepatoprotective Effects of Bauhinia racemosa Against Paracetamol and Carbon Tetrachloride Induced Liver Damage in Rats
The methanol extract of Bauhinia racemosa Lam. (Caesalpiniaceae) stem bark was investigated for the antioxidant and hepatoprotective effects in Wistar albino rats. Different groups of animals were administered with paracetamol (500 mg/kg, (p.o.) once in a day for 7 days) and carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b.wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The methanol e...
متن کاملhepatoprotective activity of aerial parts of otostegia persica against carbon tetrachloride-induced liver damage in rats
objective: to evaluate the hepatoprotective properties of otostegia persica (o. persica) ethanol extract on carbon tetrachloride-induced liver damage in rats. materials and methods: fifty adult male wistar rats were randomly divided into five groups. group i served as normal control and was given only olive oil intraperitoneally (i.p.). group ii, iii, iv, and v were administered ccl4 mixed wi...
متن کاملLiver Damage and Mortality in a Male Lewis Rat of Experimental Autoimmune Encephalomyelitis
Background and Objectives: Multiple sclerosis is an inflammatory disease of the central nervous system. This is due to migration of peripherally activated lymphocytes to central nervous system leading to inflammatory lesions. However, liver has an anti-inflammatory microenvironment. Myelin expression in the liver of transgenic mice suppresses inflammatory lesions within central nervous system. ...
متن کاملThe pretreatment effects of pentoxifylline on aflatoxin B1-induced oxidative damage in perfused rat liver
This study was conducted to investigate the hepatoprotective and antioxidant effects of pentoxifylline (PTX) against aflatoxin B1 (AFB1) exposure in perfused rat livers by evaluating damage marker enzymes, antioxidant defense systems (glutathione, GSH) and lipid peroxidation (malondialdehyde, MDA). Sixteen rats were divided randomly into four experimental groups: control, PTX, AFB1 and AFB1 + P...
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ژورنال
عنوان ژورنال: Cell Stress & Chaperones
سال: 2004
ISSN: 1355-8145,1466-1268
DOI: 10.1379/459.1